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Although amylase and lipase levels were numerically higher in the dulaglutide group during follow-up, clinically significant pancreatitis was rare, with only one case observed, likely related to gallstone disease rather than direct pharmacologic toxicity

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Cardiovascular and Endothelial Benefits GLP-1 RAs have demonstrated robust cardiovascular protection in multiple large-scale trials, including LEADER, REWIND, and SUSTAIN-6, showing reduced rates of major adverse cardiac events independent of weight loss

Administration: Tirzepatide : Once-weekly subcutaneous injection

Most of these were accidental overdoses, where people mistakenly took two doses or took the wrong dose

& Lambert, M